Table 5.
Effects of dietary L-arginine and N-carbamylglutamate supplementation on plasma proinflammatory cytokine concentrations from the peripheral blood in the IUGR suckling lambs.
| Item | CON | IUGR | IUGR+1%Arg | IUGR+0.1% NCG | P value |
|---|---|---|---|---|---|
| IL-1β (pg/mL) | 189.21 ± 17.67c | 256.38 ± 19.45a | 218.81 ± 16.33b | 216.52 ± 17.09b | 0.008 |
| TNF-α (pg/mL) | 135.34 ± 9.34c | 193.23 ± 11.56a | 159.21 ± 10.11b | 163.82 ± 12.58b | 0.015 |
| IL-6 (pg/mL) | 151.23 ± 12.35c | 227.28 ± 16.36a | 193.55 ± 13.23b | 190.98 ± 14.16b | 0.007 |
Mean values with their SEM, n = 12/group. a,b,cWithin a row, means without a common superscript letter differ (P < 0.05). IL-1β: interlukin-1β; TNF-α: tumor necrosis factor α; IL-6: interlukin-6; CON: the normal birth weight group given a control diet; IUGR: the IUGR group given a control diet; IUGR+Arg: the IUGR group given a L-arginine-supplemented diet; IUGR+NCG: the IUGR group given a N-carbamylglutamate-supplemented diet.