Table 6.
Effects of dietary L-arginine and N-carbamylglutamate supplementation on the caspase-3, caspase-8, and caspase-9 activities, and the levels of cytochrome C in the liver of IUGR suckling lambs.
Item | CON | IUGR | IUGR+1%Arg | IUGR+0.1% NCG | P value |
---|---|---|---|---|---|
Caspase-3 | 5.36 ± 0.31c | 10.14 ± 0.56a | 7.65 ± 0.47b | 7.59 ± 0.39b | 0.009 |
Caspase-8 | 5.11 ± 0.13b | 8.56 ± 0.21a | 5.08 ± 0.07b | 5.29 ± 0.11b | 0.015 |
Caspase-9 | 4.28 ± 0.21b | 7.47 ± 0.33a | 5.74 ± 0.19ab | 5.86 ± 0.21ab | 0.022 |
Cytochrome C (mmol/L) | 0.17 ± 0.02b | 0.24 ± 0.08a | 0.20 ± 0.05ab | 0.21 ± 0.03ab | 0.018 |
Mean values with their SEM, n = 12 in each group. a,b,cMean values within a row with different superscript letters were significantly different (P < 0.05). CON: the normal birth weight group given a control diet; IUGR: the intrauterine growth retardation group given a control diet; IUGR+Arg: the intrauterine growth retardation group given a L-arginine-supplemented diet; IUGR+NCG: the intrauterine growth retardation group given a N-carbamylglutamate-supplemented diet.