Table 10.

Fit summary statistics for DC (%) and drug release rate (h^1/2).

Responses	Source	Std. dev	R 2	Adj R2	Pred R2	Lack of fit	p value	PRESS	Remark
	p value						Prob > F
DC (%)	Linear	11.19	0.7904	0.7485	0.6439	0.0316	0.0004	2127.67
	2FI	10.61	0.8303	0.7738	0.5928	0.0354	0.1794	2432.95
	Quadratic	5.89	0.9594	0.9303	0.8188	0.2497	0.0067	1082.65	Suggested
	Cubic	6.69	0.9840	0.9520	0.6943	0.0375	0.2497	2230.82	Aliased
Release rate (h1/2)	Linear	1.16	0.8357	0.8028	0.6630	0.0891	0.0001	27.79
	2FI	0.78	0.9342	0.9122	0.8633	0.3355	0.0052	11.28	Suggested
	Quadratic	0.86	0.9379	0.8936	0.7051	0.2051	0.8142	24.32
	Cubic	0.67	0.9780	0.9341	0.7284	0.0373	0.2051	26.72	Aliased