Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 14;16:1744806920918057. doi: 10.1177/1744806920918057

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 6. — (a) Heat maps illustrating the most significantly changed gene expressions due to injury (No-SCS) and the effect of treatments (DTMP, HR, or LR) relative to expression in naïve animals. Each colored column is a gene. Note that DTMP modulates a larger number of genes towards the naïve state (represented by white columns) than HR and LR. (b) Heat map of genes regrouped in terms of involvement in relevant biological processes. Gray boxes indicate that therapy did not produce a significant change. The intensity of red color is proportional to the extent to down regulation relative to expression in naïve; the intensity of blue color is proportional to the extent of upregulation relative to expression in naïve. White indicates that therapy modulated expression back to levels of naïve animals. DTMP: differential target multiplexed programming; LR: low rate; HR: high rate; SCS: spinal cord stimulation.