Fig. 3.
a Hematoxylin and eosin (H&E) staining of the medial femoral condyle in DMM-operated joints. Yellow arrowheads: formation of pannus and infiltration of cells in the synovial layer. Green arrowheads: inflammatory aggregates of immune cells in the synovium. Scale bar = 250 μm. b Total joint synovitis score. Two-way repeated measures ANOVA within the same sex followed by Fisher’s LSD post hoc. *p < 0.05, DMM-operated vs. non-operated joints. #p < 0.05, HFD fat-1 vs. WT DMM-operated joints. The number (n) of the mice used in each group is indicated on plots. Data presented as mean ± SEM