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. 2020 Apr 15;13:196. doi: 10.1186/s13071-020-04064-8

Table 2.

List of MHC I epitopes with characteristic affinity and coverage

Epitope No. Epitope sequence Protein ID Starting position HLA supertype coverage Tappred binding VaxiJen score IEDB class I score No. of HLA alleles World TPC (%) Epitope conservancya in other Leishmania spp. in RefSeq database Selfb
H1-01 LLYGGIFCY E9B882 260 A1, A2, A3, A26, B58, B62 High 2.40 0.26 8 41.37 L. major, L. infantum, L. braziliensis, L. mexicana, L. guyanensis No
H1-02 KIYANWPTY E9BS02 189 A3, A26, B58, B62 High 1.41 0.25 15 63.11 L. major, L. infantum, L. mexicana No
H1-03 FVAYFRTPL E9BS02 77 A2, B7, B8, B39, B62 Medium 0.91 0.19 21 85.48 L. major, L. infantum, L. mexicana No
H1-04 FVKWNFTAF E9BI90 122 A24, A26, B7, B8, B62 Medium 1.08 0.31 16 67.98 L. infantum No
H1-05 FMHVYTTHF E9BIV4 119 A1, B8, B58, B62 Medium 0.77 0.14 19 83.44 L. major, L. infantum, L. mexicana No
H1-06 HVYTTHFAY E9BIV4 121 A1, A3, A26, B8, B58, B62 High 0.73 0.23 19 73.51 L. major, L. infantum, L. mexicana No
H1-07 YVAFVERLY E9BQ40 345 A1, A3, A26, B62 Medium 1.39 0.30 13 51.83 L. major, L. infantum, L. mexicana, L. braziliensis, L. panamensis No
H1-08 RVAAALRIY E9BUW4 58 A1, A3, A26, B58, B62 High 0.77 0.20 12 51.08 L. major, L. infantum, L. mexicana No
H1-09 ATYAALLPL E9BUW4 450 A2, B7, B58, B62 High 0.77 0.05 19 80.33 L. major, L. infantum, L. mexicana, L. braziliensis, L. panamensis No

a100% identity for absolute query cover

bidentity threshold in human for amino acids > 7 (78%)