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. 2020 Apr 15;20:217. doi: 10.1186/s12884-020-02898-9

Table 3.

Factors associated with stroke stratified by variables listed in the table by using Cox regression

Hypertensive pregnancy disorders With Without (Reference) Ratio Adjusted HR 95% CI 95% CI P
Stratified Events PYs Rate (per 105 PYs) Events PYs Rate (per 105 PYs)
Total 198 163,208.79 121.32 698 654,982.30 106.57 1.138 2.134 1.817 2.505 < 0.001
Age group (years)
 12–19 2 271.80 735.83 3 589.64 508.78 1.446 2.711 2.308 3.182 < 0.001
 20–29 64 32,914.98 194.44 87 80,370.21 108.25 1.796 3.367 2.867 3.953 < 0.001
 30–39 97 77,048.17 125.90 303 238,213.86 127.20 0.990 1.855 1.580 2.178 < 0.001
 40–49 34 18,003.53 188.85 294 137,974.59 213.08 0.886 1.661 1.415 1.950 < 0.001
 ≧50 1 34,970.30 2.86 11 197,833.99 5.56 0.514 0.964 0.821 1.132 0.276
Insured premium (USD)
  < 7200 191 125,404.75 152.31 688 466,665.85 147.43 1.033 1.937 1.649 2.273 < 0.001
 7200-13,999 5 2344.91 213.23 8 8975.42 89.13 2.392 4.484 3.818 5.264 < 0.001
  ≥ 14,000 2 35,459.13 5.64 2 179,341.03 1.12 5.058 9.481 8.073 11.129 < 0.001
DM 20 8430.94 237.22 56 42,672.99 131.23 1.808 3.389 2.885 3.978 < 0.001
HTN 54 13,688.23 394.50 99 35,172.46 281.47 1.402 2.627 2.237 3.084 < 0.001
Hyperlipidemia 13 1980.06 656.55 42 8226.33 510.56 1.286 2.411 2.052 2.830 < 0.001
Obesity 1 477.68 209.35 1 2343.45 42.67 4.906 9.196 7.830 10.795 < 0.001
Heart disease 14 5039.75 277.79 75 33,325.22 225.05 1.234 2.314 1.970 2.716 < 0.001
CKD 6 2500.94 239.91 40 23,770.74 168.27 1.426 2.673 2.276 3.137 < 0.001
Season
 Spring 52 30,039.53 173.11 146 109,482.26 133.35 1.298 2.433 2.072 2.856 < 0.001
 Summer 40 32,853.28 121.75 175 126,710.16 138.11 0.882 1.653 1.407 1.940 < 0.001
 Autumn 61 37,155.10 164.18 191 132,193.49 144.49 1.136 2.130 1.814 2.500 < 0.001
 Winter 45 63,160.87 71.25 186 286,596.39 64.90 1.098 2.058 1.752 2.416 < 0.001
Urbanization level
 1 (The highest) 75 43,701.39 171.62 225 153,595.67 146.49 1.172 2.196 1.870 2.578 < 0.001
 2 83 57,996.46 143.11 294 210,128.07 139.91 1.023 1.917 1.633 2.251 < 0.001
 3 16 10,060.20 159.04 40 46,748.29 85.56 1.859 3.484 2.967 4.090 < 0.001
 4 (The lowest) 24 51,450.75 46.65 139 244,510.27 56.85 0.821 1.538 1.310 1.806 < 0.001
Level of care
 Hospital center 96 43,471.31 220.84 301 142,056.49 211.89 1.042 1.954 1.663 2.293 < 0.001
 Regional hospital 64 50,293.76 127.25 215 183,114.94 117.41 1.084 2.032 1.730 2.385 < 0.001
 Local hospital 38 69,443.72 54.72 182 329,810.87 55.18 0.992 1.859 1.583 2.182 < 0.001

PYs Person-years; Adjusted HR Adjusted hazard ratio: Adjusted for the variables listed in Table 3; CI confidence interval