Table 6.
False-positive conditions of PSMA–PET in the diagnosis of prostate cancer
| Physiological uptake | |
| Head and neck | Lacrimal gland, parotid gland, submandibular gland |
| Abdomen | Liver, spleen, kidney, small bowel, ureter |
| Pelvis | Urinary bladder, myometrium |
| Other | Sympathetic ganglia (cervical, celiac, sacral ganglia) |
| Benign condition or disease | |
| Granuloma | Granulation tissue, keroid, sarcoidosis, active tuberculosis, anthracosis |
| Inflammation | Nodular fasciitis, bronchiectasis |
| Bone disorder | Paget’s disease, fibrous dysplasia, healing bone fracture |
| Benign tumor | Meningioma, neurogenic tumor (schwannoma), hemangioma of liver, hemangioendothelioma of liver, adrenal adenoma, pancreatic serous cystadenoma, pancreatic neuroendocrine tumor |
| Soft tissue tumor | desmoid tumor, intramuscular myxoma |
| Other | Amyloidosis |
| Malignant tumor | |
| Brain | Glioblastoma multiforme |
| Head and neck | Salivary gland ductal carcinoma, squamous cell carcinoma of oropharynx, thyroid carcinoma |
| Chest | Pulmonary adenocarcinoma, breast carcinoma |
| Abdomen | Hepatocellular carcinoma, renal cell carcinoma, gastrointestinal stromal tumor, urothelial carcinoma, colorectal carcinoma |
| Hematologic malignancy | Malignant lymphoma, multiple myeloma |