Table 2.
Sputum chemokine concentrations in asthma patients and healthy controls
| Variable | Asthma | Normal | P value |
|---|---|---|---|
| Number | 89 | 19 | |
| IL-1β (pg/ml) | 37.53 (10.59,151.78) | 38.44 (15.7, 72.94) | 0.811 |
| IL-6 (pg/ml) | 9.43 (3.44, 40.61) | 4.36 (2.95, 13.36) | 0.013 |
| IL-8 (pg/ml) | 3099.66 (278.93, 8805.46) | 3428.69 (612.39, 12,145.63) | 0.164 |
| IL-10 (pg/ml) | 0.78 (0.54, 1.36) | 1.35 (0.92, 1.61) | 0.052 |
| IL-17A (pg/ml) | 6.16 (1.10, 15.09) | 53.95 (18.02, 81.59) | < 0.001 |
| IL-23 (pg/ml) | 8.10 (3.57, 20.99) | 19.33 (8.63, 38.75) | 0.034 |
| TNF-α (pg/ml) | 0.49 (0.32, 0 .79) | 0.46 (0.34, 0.67) | 0.404 |
| IL-35 (ng/ml) | 4.89 (2.97, 22.75) | 6.01 (4.09, 30.47) | 0.247 |
| MCP-1 (pg/ml) | 118.20 (17.87, 280.02) | 25.45 (3.25, 70.32) | 0.003 |
Data are expressed as median (IQR). Data were analyzed using a Mann-Whitney U test and adjusted for age. IL Interleukin, TNF Tumor necrosis factor, MCP monocyte chemoattractant protein