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. 2020 Apr 15;20:125. doi: 10.1186/s12935-020-01199-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — High expression levels of KIF15 is related with several clinicopathological characteristics, and predicts poor prognosis of GC patients. a KIF15 expression level was higher in elder (> 67) GC patients (P < 0.001). b KIF15 expression level was markedly increased in low GC tumor grade (G1/G2) than in high GC tumor grade (G3) (P < 0.001). c, d Regression analysis of correlation of BIRC5, HSPD1 gene expression levels and KIF15 expression level in GC tissues (Spearman r = 0.74 and 0.69 respectively, P < 0.001). e TNFRSF1A expression was inversely correlated with KIF15 expression in TCGA database (Spearman r = − 0.43, P < 0.001). f Kaplan–Meier curves of overall survival was analyzed according to KIF15 expression levels in 122 patients with GC. The result showed that higher expression level of KIF15 represents poor prognosis (P < 0.01)