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. 2019 Aug 9;10(11):1867–1870. doi: 10.1039/c9md00233b

Table 1. Comparative solubility of Pritelivir free and mesylate salt in the different excipients.

Excipient Saturated solubility (mg ml–1)
Pritelivir free base Pritelivir mesylate salt
Water BLOQ a 1.2
pH 3.5 buffer 0.1 mg 1.3
pH 4.5 buffer 0.1 0.4
pH 5.5 buffer 0.1 0.2
pH 7.0 buffer 0.1 BLOQ a

aBLOQ: below limit of detection.