Figure 3.

MfSAP1 degrades human extracellular matrix proteins. (A–E) ECM protein degradation, as assessed by SDS-PAGE, after MfSAP1 was incubated with each purified ECM protein at varying substrate to enzyme ratios. (F) Cartoon of the decellularization and protease treatment (top). Degradation of whole dermal fibroblast (left) and keratinocyte (right) ECM at different MfSAP1 concentrations by SDS-PAGE analysis. Representative SDS-PAGE images are shown for a total of at least 2 independent experiments.