Skip to main content
. Author manuscript; available in PMC: 2020 Apr 16.
Published in final edited form as: Peptides. 2019 Jul 20;119:170119. doi: 10.1016/j.peptides.2019.170119

Table 3.

AMP cytotoxicity and hemolytic activity.

IC50 (μg/mL) HC50 (μg/mL)
Peptide sequence Peptide code HEK-293a Human red blood cells
GLFDVIKKVASVIGGL AMP-001/Cit 1.1 20.98 > 32
GLFDVI(Orn)(Orn)VASVIGGL AMP-006 > 32 > 32
GLFDVIRRVASVIGGL AMP-012 17.64 18.2
GLFDVIRKVASVIGGL AMP-013 21.26 > 32
GLFEVIKKVASVIGGL AMP-015 > 32 > 32
GLWDVIKKVASVIGGL AMP-016 > 32 16.85
GLWRVIRKVASVIGGL AMP-017 18.10 26.7
PhenylGlyLWDVIRKVASVIGGL AMP-018 19.44 > 32
GL(Biphenylalanine)DVIKKVASVIGGL AMP-019 17.04 > 32
GL(1-Nap)DVIKKVASVIGGL AMP-020 16.85 > 32
SarLWDVIRKVASVIGGL AMP-021 30.90 > 32
a

Human embryonic kidney cells (ATCC CRL-1573). Assays were performed by The Community for Antimicrobial Drug Discovery (CO-ADD), Australia.