Table 7.
National Paediatric Rheumatological Database (NPRD) with a uveitis add-on module in Germany (2002–2016). Uveitis-related eye complications at follow-up documentation. Data as provided in uveitis documentation
| Follow-up documentation. Uveitis-related eye complications per patient, n (%) |
Group I. Uveitis, ANA-positive, no JIA, N = 56 |
Group II. Uveitis manifestation after JIA disease onset*, N = 56 |
Group III. Uveitis manifestation before JIA disease onset*, N = 37 |
p value† | Significant pairwise comparisons‡ | |||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | |||
| Any complication | 29 | 56.9 | 20 | 37.7 | 19 | 57.6 | 0.086 | |
| Band keratopathy | 7 | 13.7 | 2 | 3.8 | 9 | 27.3 | 0.072 | II vs. III |
| Glaucoma | 4 | 7.8 | 0 | 0.0 | 0 | 0.0 | 0.031 | |
| Synechiae | 16 | 31.4 | 13 | 24.5 | 11 | 33.3 | 0.622 | |
| Ocular hypotony | 0 | 0.0 | 0 | 0.0 | 2 | 6.1 | 0.041 | |
| Retinal detachment | 1 | 2.0 | 0 | 0.0 | 1 | 3.0 | 0.500 | |
| Papille edema | 3 | 5.9 | 2 | 3.8 | 2 | 6.1 | 0.852 | |
| Iris rubeosis | 3 | 5.9 | 0 | 0.0 | 1 | 3.0 | 0.205 | |
| Cataract | 10 | 19.6 | 5 | 9.4 | 6 | 18.2 | 0.309 | |
| Vitreous opacities | 5 | 9.8 | 4 | 7.6 | 2 | 6.1 | 0.816 | |
| Macular edema | 2 | 3.9 | 2 | 3.8 | 1 | 3.0 | 0.976 | |
| Amblyopia/strabism | 3 | 5.9 | 0 | 0.0 | 2 | 6.1 | 0.194 | |
| Other complications | 2 | 3.9 | 5 | 9.4 | 3 | 9.1 | 0.503 | |
| Treatment-related eye complications | 1 | 2.0 | 1 | 1.9 | 1 | 3.0 | 0.931 | |
†Group effect for the proportion of treated patients by chi-squared test for categorical variables
‡Pairwise comparisons for the proportion of treated patients with correction for multiple comparisons by Bonferroni (chi-squared test)
*Initial uveitis diagnosis