Table 1.
The expression levels of bone cell markers (GZZSZTW vs. Blank)
| Gene name | Blank (FPKM) | GZZSZTW (FPKM) | log2 fold change (GZZSZTW/Blank) | p value |
|---|---|---|---|---|
| Osteoblast markers | ||||
| Collagen alpha-1(I) chain (Col1a1) | 198.95 | 66.96 | − 1.57 | 0 |
| Alkaline phosphatase, (Alpl) | 15.81 | 5.33 | − 1.57 | 6.62E−20 |
| Bone sialoprotein 2 (Ibsp) | 91.97 | 17.38 | − 2.40 | 2.20E−150 |
| Osteocalcin (Bglap) | 872.04 | 147.20 | − 2.57 | 6.10E−313 |
| Osteopontin (Spp1) | 96.37 | 34.42 | − 1.49 | 5.87E−64 |
| Osteomodulin (Omd) | 7.34 | 0.75 | − 3.29 | 1.52E−16 |
| Decorin (Dcn) | 56.87 | 19.21 | − 1.57 | 2.30E−45 |
| Osteoclast markers | ||||
| Tartrate-resistant acid phosphatase type 5 (Acp5) | 103.22 | 13.98 | − 2.88 | 6.00E−147 |
| Cathepsin K (Ctsk) | 82.80 | 6.46 | − 3.68 | 3.00E−150 |
| Nuclear factor of activated T-cells, cytoplasmic 3 (Nfatc3) | 6.77 | 3.28 | − 1.05 | 5.21E−12 |
| Myc proto-oncogene protein (Myc) | 14.37 | 6.47 | − 1.15 | 1.13E−11 |
| Osteocyte markers | ||||
| Podoplanin (Pdpn) | 3.33 | 1.10 | − 1.60 | 8.21E−04 |
| Dentin matrix acidic phosphoprotein 1 (Dmp1) | 45.75 | 5.78 | − 2.98 | 7.15E−132 |
| Sclerostin (Sost) | 11.75 | 0.57 | − 4.37 | 2.85E−11 |
| Metalloendopeptidase homolog PEX (Phex) | 0.82 | 0.12 | − 2.77 | 9.62E−05 |
| Matrix extracellular phosphoglycoprotein (Mepe) | 40.91 | 4.96 | − 3.04 | 2.53E−73 |
| Dickkopf-related protein 1 (Dkk1) | 3.65 | 0.37 | − 3.30 | 3.92E−11 |