Table 1.
Demographic characteristics, preoperative and intraoperative data of patients
| Variable | Total (n = 76) |
NDF (n = 50) |
TND (n = 16) |
Stroke (n = 10) |
P value |
|---|---|---|---|---|---|
| Male | 61 (80.3) | 40 (80.0) | 15 (97.8) | 6 (60.0) | 0.109 |
| Age (year) | 45.8 ± 9.9 | 45.3 ± 10.6 | 48.1 ± 9.0 | 47.0 ± 8.4 | 0.799 |
| BMI (kg/m2) | 27.4 ± 4.6 | 27.4 ± 4.2 | 27.8 ± 5.8 | 26.8 ± 4.9 | 0.863 |
| Hypertension | 60 (78.9) | 41 (82.0) | 12 (75.0) | 7 (70.0) | 0.634 |
| Diabetes mellitus | 3 (3.9) | 3 (6.0) | 0 | 0 | 0.444 |
| Marfan syndrome | 1 (1.3) | 0 | 1 (6.3) | 0 | 0.150 |
| Smoking history | 33 (43.4) | 21 (42.0) | 9 (56.3) | 3 (30.0) | 0.397 |
| LVEF (%) | 62.2 ± 4.9 | 62.3 ± 4.5 | 60.7 ± 6.5 | 63.9 ± 3.6 | 0.258 |
| White blood cell count (109/l) | 12.0 ± 3.0 | 11.5 ± 3.0 | 12.99 ± 3.6 | 12.8 ± 1.8 | 0.155 |
| Serum creatinine (umol/l) | 84.7 ± 31.6 | 78.1 ± 20.4 | 105.9 ± 51.6 | 84.4 ± 24.3 | 0.142 |
| Primary entry tear | |||||
| Unknown | 14 (18.4) | 7 (14.0) | 4 (25.0) | 3 (30.0) | 0.367 |
| Ascending aorta | 57 (75.0) | 38 (76.0) | 12 (75.0) | 7 (70.0) | 0.923 |
| Aortic arch | 5 (6.6) | 5 (10.0) | 0 | 0 | 0.993 |
| Coronary artery involvement | 20 (26.3) | 17 (34.0) | 1 (6.3) | 2 (20.0) | 0.628 |
| Aortic root repair | 0.606 | ||||
| Ascending aorta replacement | 50 (65.8) | 31 (62.0) | 12 (75.0) | 7 (70.0) | |
| Bentall procedure | 26 (34.2) | 19 (38.0) | 4 (25.0) | 3 (30.0) | |
| Lowest nasopharyngeal temperature (°C) | 23.5 ± 0.8 | 23.5 ± 0.8 | 23.7 ± 0.7 | 23.7 ± 0.5 | 0.412 |
| CPB time (min) | 205.8 ± 43.2 | 199.5 ± 41.6 | 223.9 ± 45.3 | 207.8 ± 43.6 | 0.143 |
| Cross-clamp time (min) | 114.2 ± 30.5 | 109.9 ± 30.5 | 129.5 ± 29.8 | 111.0 ± 26.5 | 0.724 |
| Circulatory arrest time (min) | 22.9 ± 7.5 | 22.0 ± 7.5 | 26.4 ± 7.6 | 22.2 ± 6.1 | 0.737 |
| Intraoperative transfusion of PRBCs | 44 (57.9) | 27 (54.0) | 12 (75.0) | 5 (50.0) | 0.589 |
| Intraoperative transfusion of FFP | 38 (50.0) | 24 (48.0) | 10 (62.5) | 4 (40.0) | 0.500 |
| Intraoperative transfusion of platelets | 5 (6.9) | 3 (6.0) | 2 (12.5) | 0 | 0.993 |
| cIMT (mm) | 0.93 ± 0.16 | 0.87 ± 0.13 | 0.99 ± 0.13 | 1.12 ± 0.19 | < 0.001 |
| cIMT (mm) > 0.9 | 35 (46.5) | 15 (30.0) | 12 (75.0) | 8 (80.0) | < 0.001 |
Continuous data are presented as the mean ± standard deviation and categorical data as number (percentage)
Abbreviations: NDF neurological dysfunction-free, TND temporary neurological dysfunction, BMI body mass index, LVEF left ventricular ejection fraction, CABG coronary artery bypass grafting, CPB cardiopulmonary bypass, PRBCs packed red blood cells, FFP fresh-frozen plasma, cIMT carotid intima–media thickness