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. 2020 Apr 15;12:33. doi: 10.1186/s13098-020-00539-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — PVT1 and WT1 were up-regulated in the serum of DN patients and HG-induced MCs. PVT1 expression by qRT-PCR in 34 serum samples from patients with DN and 30 serum samples from healthy controls (a), HG-induced MCs (b). WT1 mRNA level by qRT-PCR in 34 serum samples from patients with DN and 30 serum samples from healthy controls (c), HG-induced MCs (d). e, f WT1 expression by western blot in 3 serum samples from DN patients, 3 normal serum samples, normal MCs, and HG-induced MCs. *P < 0.05