Table 1.

Performance of the modified 2010 criteria (incorporating the concordance serological score proposed by Regueiro et al.) compared to the original ACR/EULAR 2010 criteria for RA, with RA according to the 1987 criteria at 1 year as the gold standard

Serological component	Sensitivity, % (95%CI)	Specificity, % (95%CI)	PPV, % (95%CI)	NPV, % (95%CI)	OR (95%CI)
2010 ACR/EULAR (quantitative)	84.5 (82.4–86.7)	68.8 (65.9–71.7)	74.9 (72.4–77.4)	80.2 (77.4–82.9)	12.1 (9.7–15.0)
Modified (qualitative)	82.3 (80.0–84.7)	71.6 (68.8–74.5)	76.2 (73.7–78.7)	78.7 (75.9–81.4)	11.8 (9.5–14.6)

PPV positive predictive value, NPV negative predictive value, OR odds ratio, CI confidence interval