TABLE 10-13.

BILIARY ATRESIA VERSUS NEONATAL HEPATITIS

IMAGING STUDY	BILIARY ATRESIA	NEONATAL HEPATITIS	OTHER DISORDERS OF INTEREST
Ultrasound	Nonvisualization of gallbladder, common bile duct	Normal gallbladder and common bile duct; echogenic liver	Choledochal cyst would show dilation of bile ducts.
DISIDA scan	Good or delayed uptake without excretion into the bowel	Delayed uptake of trace with some excretion into the bowel	Spontaneous rupture of biliary tree would show bile leak.
Liver biopsy	Proliferation of the bile ducts, bile plugs in the ducts, fibrosis of portal tracts or hepatocytes, cirrhosis	Inflammation of the hepatic parenchyma, cholestasis, possible giant cell transformation, hepatic acini (rosettes), variable inflammation	PFICs would show chronic cholestasis without ductular proliferation, cirrhosis, variable portal fibrosis and giant cell transformation

PFIC, Progressive Familial Intrahepatic Cholestasis