Table 61-2.
Common Clinical Signs in Dogs with Liver Disease
| Liver Disease with Relative Frequency (%) | PERCENTAGE OF DOGS AFFECTED BY DISEASE WITH SIGNS |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Apathy, Depression | Inappetence | Reduced Endurance | Vomiting | Diarrhea | Weight Loss | Hepatic Encephalopathy | Polyuria/Polydipsia | Dysuria | Anesthesia Intolerance | Acholic Feces | Distended Abdomen | Retarded Growth | |
| Acute hepatitis (3) | 44 | 49 | − | 61 | 21 | 12 | − | 11 | − | − | − | − | − |
| Chronic hepatitis (10) | 18 | 29 | 14 | 43 | 33 | 39 | − | 49 | − | − | − | − | − |
| Cirrhosis (7) | 25 | 53 | 39 | 61 | 37 | 58 | 9 | 56 | − | − | − | 55 | − |
| Lobular dissecting hepatitis (2) | 58 | 21 | 29 | 32 | 20 | 45 | 22 | 39 | − | − | − | 65 | − |
| Reactive hepatitis (25) | 10 | 34 | − | 48 | 77 | 39 | − | 9 | − | − | − | − | − |
| Destructive cholangiolitis (1) | 76 | 82 | − | 68 | 21 | 66 | − | 49 | − | − | 9 | 8 | − |
| Portosystemic shunt (16) | 99 | 68 | 62 | 31 | 12 | 81 | 91 | 52 | 3 | 9 | − | − | 39 |
| Portal vein thrombosis (1) | 25 | 10 | − | 38 | 44 | 15 | 5 | 32 | − | − | − | 33 | − |
| Portal vein hypoplasia (4) | 49 | 13 | 22 | 16 | 21 | 14 | 38 | 45 | − | − | − | 60 | 8 |
| Liver cell carcinoma (4) | 15 | 26 | 18 | 74 | 14 | 32 | − | 19 | − | − | − | 25 | − |
| Metastatic tumor (10) | 24 | 54 | 17 | 67 | 27 | 60 | − | 38 | − | − | − | 14 | − |
| Malignant lymphoma (14) | 18 | 75 | 32 | 70 | 21 | 85 | − | 55 | − | − | − | 5 | − |
| Cholecystitis/choleliths (1) | − | 65 | − | 93 | 19 | 30 | − | − | − | − | − | − | − |
| Extrahepatic cholestasis (2) | 10 | 72 | − | 81 | 37 | 54 | − | 46 | − | − | 16 | − | − |
Figures are from the Utrecht University Clinic population. The relative frequencies are based on 2500 referred cases.