TABLE 33.1.
World Health Organization Classification System for Canine Lymphoma
| Category | Percentage |
||
|---|---|---|---|
| Seelig et al96 (n = 3 data sets) |
Vezzali et al98 (n = 123) |
University of Wisconsin (n = 122) |
|
| B-Cell Neoplasms | 69 | 78.9 | 59.0 |
| Precursor B lymphoblastic leukemia/lymphomaa | — | 2.4 | 8.2 |
| B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma | — | 2.4 | 0.8 |
| Lymphocytic lymphoma—intermediate type | — | 0.8 | — |
| Lymphoplasmacytic lymphoma | — | 3.3 | 0.8 |
| Mantle cell lymphoma | 2 | 1.6 | — |
| Follicular center cell lymphomas | — | 2.4 | — |
| Marginal zone lymphoma (splenic, nodal, mucosa-associated lymphoid tissue) | 8 | 3.3 | 2.5 |
| Plasma cell myeloma/plasmacytoma | — | 16.3 | 9.8 |
| Diffuse large cell lymphoma | 52 | 33.3 | 24.6 |
| T-cell–rich, B-cell lymphoma | — | 0.8 | — |
| Large cell immunoblastic lymphoma | — | 10.6 | 10.7 |
| Mediastinal (thymic) large B-cell lymphoma | — | 0.8 | — |
| Burkitt’s lymphoma/leukemia | — | 0.8 | 1.6 |
| Other B cell | 8d | — | — |
| T-Cell and Natural Killer (NKb) Cell Lymphomas | 31 | 21.1 | 41.0 |
| Precursor T lymphoblastic lymphoma/leukemiaa | 3 | 6.5 | 9.8 |
| T-cell chronic lymphocytic leukemia (CLL) | — | 3.3 | 0.8 |
| Intestinal T-cell lymphoma | — | 4.1 | 4.1 |
| Mycosis fungoides/Sézary syndrome | — | 1.6 | 11.5 |
| Cutaneous nonepitheliotropic lymphoma | — | 3.3 | — |
| Anaplastic large cell lymphoma | — | — | 0.8 |
| Peripheral T-cell lymphoma-not otherwise specified | 15 | 2.4 | 13.1c |
| T-zone lymphoma | 4 | ||
| Other T cell | 7d | — | — |
| Other | 3d | ||
a
Acute leukemias and lymphoblastic lymphomas of both B and T derivation are also classified as lymphoid “precursor neoplasms.”
b
Non-B, non-T lymphomas.
c
Includes T-zone lymphoma in this data set.
d
Other in Seelig include those not otherwise subclassified.