TABLE 33.9.
General Characteristics of the Most Commonly Encountered Anatomic Forms of Lymphoma in Cats
| Anatomic Form | Relative Frequency | Median Age (yr) | Immuno-Phenotype (Generally) | FeLV Antigenicity | Local versus Diffuse/Multicentric | Biologic Behavior | General Prognosis |
|---|---|---|---|---|---|---|---|
| Alimentary/ Gastrointestinal LGAL I/HGAL LGL |
Common Uncommon Uncommon |
10–13 12 9 |
T-cell, small B-cell, large T-cell, large |
Rare Rare Rare |
Diffuse Generally Diffuse Generally Diffuse |
Indolent Aggressive Aggressive |
Good Poor–Fair Poor |
| Nasal | Uncommon | 9–10 | B cell (75%) | Rare | Local common | More indolent | Good–Fair |
| Mediastinal | Uncommon | 2–4 | T-cell, large | More common | Local common | Indolent or aggressive forms | Fair–Poor |
| Peripheral nodal Non-Hodgkin’s Hodgkin’s-like |
Uncommon Rare |
3–4 11 |
B-cell (75%), large T-cell rich B-cell, large |
More common Rare |
Multicentric Local initially |
Aggressive Indolent |
Fair–Poor Good– Fair |
| Laryngeal/Tracheal | Rare | 9 | ID | Rare | Local common | ID | Fair–Good |
| Renal | Uncommon | 9 | B-cell | Rare | Multicentric | Aggressive | Poor–Fair |
| CNS | Rare | 4–10 | ID | Rare | Multicentric | Aggressive | Poor |
| Cutaneous | Rare | 10–13 | T-cell | Rare | Local initially | Indolent to aggressive | Fair |
| Subcutaneous | Rare | 10–13 | B-cell, large | Rare | Local initially | Aggressive | Fair |
| Ocular (PSOL) | Rare | 10–11 | B-cell | Rare | Local | Often indolent | Good–Fair |
Common = >50% of clinical presentations; Moderate = 20%–50% of clinical presentations;
Uncommon = 5%–20% of clinical presentation; Rare = <5% of clinical presentations.
ID, Insufficient data; I/HGAL, intermediate-/high-grade alimentary lymphoma; LGAL, low-grade alimentary lymphoma; LGL, = large granular lymphoma; PSOL, presumed solitary ocular lymphoma.