TABLE 33.12.
COP Protocol for Lymphoma in Cats
| Drug | Frequency of Drug Delivery |
|---|---|
| Cyclophosphamide: 250–300 mg/m2, POa | Given every 3 weeks on the day after vincristine |
| Vincristine: 0.7 mg/m2, IV | Given weekly on weeks 1, 2, 3, and 4, then given every 3 weeks thereafter on the days before cyclophosphamide. Discontinue if in remission at 1 year. |
| Prednisolone: 1–2 mg/kg, PO | Given daily for 1 year. |
Note: A complete blood count (CBC) should be performed before each chemotherapy. If neutrophils are <1500 cells/μL, wait 5–7 days, repeat CBC, then administer the drug if neutrophils have risen above the 1500 cell/μL cutoff.
a
Some divide the cyclophosphamide over 3 consecutive days.