Table 1.
Demographic information of groups, test results and CRS-R/NCS assessments of UWS patients.
| Protocol result | CRS-R/NCS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Patient | Diagnosis | Age | Etiology | Time from event (days) | CR response | Week I | Week II | Week III | Week IV | Final diagnosis |
| 1 | UWS | 50–55 | HEM | 27 | 1 | 4/3 | 4/3 | 8/4 | 8/4 | MCS |
| 2 | 60–65 | HEM | 39 | 1 | 6/5 | 7/7 | 9/6 | 11/7 | MCS | |
| 3 | 16–20 | TBI | 28 | 1 | 4/1 | 4/1 | 7/3 | 8/3 | MCS | |
| 4 | 66–70 | TBI | 25 | 1 | 6/5 | 6/5 | 10/8 | 12/7 | MCS | |
| 5 | 60–65 | TBI | 26 | 1 | 4/3 | 5/3 | 9/5 | 8/5 | MCS | |
| 6 | 30–35 | TBI | 21 | 1 | 5/2 | 5/2 | 8/4 | 10/5 | MCS | |
| 7 | 66–70 | TBI | 39 | 1 | 4/4 | 8/3 | 8/5 | 8/5 | MCS | |
| 8 | 16–20 | TBI | 25 | 1 | 4/2 | 8/3 | 14/5 | 14/7 | MCS | |
| 9 | 36–40 | ANOX | 21 | 1 | 4/3 | 6/2 | 4/3 | 6/4 | UWS | |
| 10 | 66–70 | HEM | 23 | 0 | 4/4 | 7/3 | 4/3 | 7/5 | UWS | |
| 11 | 40–45 | HEM | 55 | 0 | 4/1 | 4/1 | 4/1 | 4/1 | UWS | |
| 12 | 46–50 | HEM | 32 | 0 | 4/1 | 3/4 | 3/3 | 5/4 | UWS | |
| 13 | 56–60 | HEM | 24 | 0 | 5/3 | 4/3 | 5/3 | 5/3 | UWS | |
| 14 | 56–60 | HEM | 35 | 0 | 4/3 | 4/3 | 4/3 | 6/3 | UWS* | |
| 15 | 56–60 | HEM | 39 | 0 | 3/1 | 5/3 | 5/3 | 6/3 | UWS | |
| 16 | 66–70 | HEM | 58 | 0 | 5/3 | 5/3 | 6/3 | 6/3 | UWS | |
| 17 | 60–65 | HEM | 34 | 0 | 5/3 | 6/3 | 5/3 | 4/4 | UWS | |
| 18 | 56–60 | TBI | 30 | 0 | 5/1 | 5/4 | 4/3 | 5/4 | UWS | |
| 19 | 46–50 | TBI | 23 | 0 | 2/1 | 7/5 | 5/3 | 5/5 | UWS | |
| 20 | 60–65 | TBI | 33 | 0 | 6/3 | 6/3 | 6/3 | 6/3 | UWS | |
| 21 | 56–60 | TBI | 36 | 0 | 5/2 | 5/2 | 5/2 | 7/5 | UWS | |
| 22 | 20–25 | TBI | 27 | 0 | 5/2 | 6/2 | 6/4 | 6/4 | UWS | |
| 23 | 20–25 | TBI | 27 | 0 | 4/3 | 6/4 | 6/3 | 5/3 | UWS | |
| 24 | 26–30 | TBI | 28 | 0 | 6/3 | 5/4 | 5/4 | 7/4 | UWS | |
| 25 | 26–30 | TBI | 23 | 0 | 6/5 | 6/5 | 7/6 | 7/5 | UWS | |
| 26 | 20–25 | TBI | 21 | 0 | 5/3 | 6/3 | 7/4 | 7/4 | UWS* | |
| 27 | 66–70 | ANOX | 25 | 0 | 5/4 | 6/4 | 6/5 | 7/7 | UWS | |
| 28 | 60–65 | ANOX | 23 | 0 | 5/1 | 5/2 | 4/2 | 4/2 | UWS | |
| 29 | 26–30 | ANOX | 31 | 0 | 3/3 | 3/3 | 6/3 | 6/3 | UWS | |
| 30 | 40–45 | ANOX | 37 | 0 | 4/1 | 5/2 | 6/2 | 5/3 | UWS | |
| 1 | HC | 50–55 | ||||||||
| 2 | 20–25 | |||||||||
| 3 | 20–25 | |||||||||
| 4 | 30–35 | |||||||||
| 5 | 36–40 | |||||||||
| 6 | 26–30 | |||||||||
| 7 | 36–40 | |||||||||
| 8 | 20–25 | |||||||||
| 9 | 36–40 | |||||||||
| 10 | 36–40 | |||||||||
| 11 | 40–45 | |||||||||
| 12 | 26–30 | |||||||||
| 13 | 40–45 | |||||||||
MCS, Minimally Conscious State; UWS, Unresponsive Wakefulness Syndrome; UWS*, patients without CR that change the level of consciousness after 6 months from the onset; HEM, Hemorrhagic; TBI, Traumatic Brain Injury; ANOX, Anoxic; CR, Conditional Response (0 = absent; 1 = present); CRS-R, Coma Recovery Scale–Revised; NCS, Nociception Coma Scale; Week (I-IV), Successive weeks during which the patients were assessed by CRS-R and NCS. In bold patients with Trace Conditioning.