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Depletion of PAK1 decreased the proliferation of pancreatic cells. Knockdown of PAK1 in BxPC-3 and PANC-1 cells was confirmed by (A) Q-PCR and (B) Western blot. (C) PAK1 silencing retarded the proliferation of BxPC-3 and PANC-1 cells. shControl and shPAK1 transfected cells were subjected to MTT assay for 3 days after transfection. Data are represented as mean ± SD, n = 3. ***P < 0.001 compared with shControl cells.
