. Author manuscript; available in PMC: 2020 Apr 16.

Published in final edited form as: Calcif Tissue Int. 2019 Sep 3;105(6):660–669. doi: 10.1007/s00223-019-00603-3

Table 2:

Fold changes in mRNA expression of BAPN-treated samples relative to controls.

Target Gene	0.25mM	1.0mM	2.0mM	5.0mM	10mM
LOX	0.737 (0.625 – 0.969)	1.138 (0.880 – 1.508)	0.934 (0.716 – 1.255)	1.402 (1.065 – 1.761)	1.469 (1.178 – 1.809)
BMP-1	2.072 (1.506 – 2.902)^*	2.705 (2.120 – 3.529)^*	2.622 (1.861 – 3.814)^*	2.212 (1.700 – 2.992)^*	2.299 (1.762 – 3.093)^*
POST	1.207 (0.616 – 2.274)	3.443 (1.716 – 6.963)^*	4.407 (2.165 – 8.833)^*	6.058 (3.328 – 11.738)^*	10.468 (5.079 – 20.207)^*
COL1A1	1.327 (0.907 – 1.991)	1.835 (1.202 – 2.892)^*	2.179 (1.495 – 3.448)^*	1.724 (1.056 – 2.736)	1.897 (1.311 – 2.988)^*
COL1A2	1.517 (0.967 – 2.189)	1.652 (1.096 – 2.462)^*	1.944 (1.335 – 3.075)^*	1.395 (0.871 – 2.421)	1.892 (1.239 – 2.892)^*

Fold changes reported with 95% confidence interval (n=3 for LOX, n=5 for all other targets).

Indicates statistically significant changes (p<0.05).