Table 1.
IC50 and CI values of mixed liposomes in L02 and HepG2 cells (μg/mL, mean ± SD, n = 3).
Molar ratio | L02 cells |
HepG2 cells |
||||||
---|---|---|---|---|---|---|---|---|
Lips-P/TP |
GLips-P/TP |
Lips-P/TP |
GLips-P/TP |
|||||
IC50 (μg/mL) | CI | IC50 (μg/mL) | CI | IC50 (μg/mL) | CI | IC50 (μg/mL) | CI | |
1:0 | 0.97±0.23 | – | 0.63±0.10* | – | 0.37±0 0.04** | – | 0.26±0.03** | – |
3:1 | 0.63±0.06 | 0.69 | 0.32±0.015** | 0.48 | 0.26±0.01** | 0.61 | 0.09±0.01** | 0.28 |
1:1 | 1.06±0.17 | 0.74 | 0.81±0.16 | 0.96 | 0.62±0.04** | 1.06 | 0.40±0.03** | 0.95 |
1:3 | 1.71±0.32 | 0.95 | 1.07±0.24** | 0.99 | 0.79±0.19** | 1.10 | 0.71±0.06** | 1.25 |
0:1 | 3.66±1.14 | – | 2.17±0.16* | – | 2.35±0.40* | – | 1.56±0.33** | – |
*P < 0.05, **P < 0.01 vs. Lips-P/TP (one-sample t-test). –Not applicable.