Table 3.

Pharmacokinetic parameters of SLB, SLB micelles and SLB-HA micelles.

Sample	SLB	SLB micelle	SLB-HA micelle
Dose (mg/kg)	10.0	10.0	10.0
Cmax (μg/mL)a	2.64 ± 0.3	8.04 ± 0.7*	21.2 ± 1.5*&
Tmax (min)b	5	5	5
AUC (h·μg/L)c	3.11	11.72*	97.52*&
AUC/dose (h·kg/L)	3.11 × 10−4	1.172 × 10−3*	9.752 × 10−3*&
t1/2 (min)	20.1	25.6*	104.3*&

AUC, area under the curve. All values are mean ± SD (n = 5).

*P < 0.01 vs. SLB; ^&P < 0.01 vs. SLB micelles.