Jacobs 1968.
Methods | RCT; double‐blind; participants were allotted the next serial number in their diagnostic category and given the appropriate numbered bottle. |
Participants | Population and setting: 110 participants with clinically diagnosed prolapsed intervertebral disc with or without radicular pain attending an outpatient clinic, maximum 60 years of age Inclusion criteria: acute or chronic LBP, age < 60 years Exclusion criteria: neoplastic, metabolic, or other bone disease, pregnancy, diabetes, epilepsy, peptic ulcer |
Interventions |
NSAID (i): indomethacin 25 mg capsules, 3 capsules per day for 2 days, 4 capsules per day next 5 days (N = 25 with nerve root pain, and N = 30 without nerve root pain) Reference treatment (ii): placebo capsules (N = 25 with nerve root pain, and N = 30 without nerve root pain) |
Outcomes | Data on effectiveness in graphs; adverse events |
Notes | 1. Both acute and acute flare of chronic LBP included, no distinction made; no subgroup analysis 2. We were unable to find contact details to ask for clarification (21 October 2019) |