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. 2020 Apr 16;2020(4):CD013581. doi: 10.1002/14651858.CD013581

Jacobs 1968.

Methods RCT; double‐blind; participants were allotted the next serial number in their diagnostic category and given the appropriate numbered bottle.
Participants Population and setting: 110 participants with clinically diagnosed prolapsed intervertebral disc with or without radicular pain attending an outpatient clinic, maximum 60 years of age
 Inclusion criteria: acute or chronic LBP, age < 60 years
 Exclusion criteria: neoplastic, metabolic, or other bone disease, pregnancy, diabetes, epilepsy, peptic ulcer
Interventions NSAID (i): indomethacin 25 mg capsules, 3 capsules per day for 2 days, 4 capsules per day next 5 days (N = 25 with nerve root pain, and N = 30 without nerve root pain)
Reference treatment (ii): placebo capsules (N = 25 with nerve root pain, and N = 30 without nerve root pain)
Outcomes Data on effectiveness in graphs; adverse events
Notes 1. Both acute and acute flare of chronic LBP included, no distinction made; no subgroup analysis
2. We were unable to find contact details to ask for clarification (21 October 2019)