Table 2.
Medication | Integrated Stepped Alcohol Treatment, N=63 No. (%) | Treatment as Usual, N=65 No. (%) | p valuea |
---|---|---|---|
Any alcohol treatment medicationa | |||
Baseline | 11 (17.46%) | 10 (15.38%) | 0·75 |
Week 4 | 20 (31.75% | 4 (6.15%) | 0.0002 |
Week 24 | 32 (50.79%) | 17 (26.15%) | 0·004 |
Week 52 | 16 (25.40%) | 13 (20.00%) | 0·47 |
Disulfiram | |||
Baseline | 0 (0·0%) | 0 (0·0%) | |
Week 4 | 1 (1.59%) | 0 (0.00%) | 0·49 |
Week 24 | 2 (3·17%) | 0 (0·0%) | 0·24 |
Week 52 | 0 (0·0%) | 0 (0·0%) | n/a |
Acamprosate | |||
Baseline | 0 (0·0%) | 0 (0·0%) | |
Week 4 | 1 (1.59%) | 0 (0.0%) | 0·49 |
Week 24 | 6 (9·52%) | 0 (0.0%) | 0·01 |
Week 52 | 0 (0%) | 0 (0.0%) | n/a |
Naltrexone | |||
Baseline | 0 (0.0%) | 1 (1·54%) | |
Week 4 | 12 (19.1%) | 0 (0.0%) | 0.0002 |
Week 24 | 20 (31·75%) | 5 (7·69%) | 0.0007 |
Week 52 | 4 (6·35%) | 5 (7·69%) | 1·00 |
Topiramate | |||
Baseline | 0 (0·0%) | 0 (0.0%) | |
Week 4 | 1 (1.59%) | 0 (0.0%) | 0·49 |
Week 24 | 0 (0.0%) | 1 (1·54%) | 1·00 |
Week 52 | 0 (0.0%) | 1 (1·54%) | 1·00 |
Baclofen | |||
Baseline | 3 (4·8%) | 1 (1·54%) | |
Week 4 | 1 (1·59%) | 0 (0.0%) | 0·49 |
Week 24 | 1 (1·59%) | 1 (1·54%) | 1·00 |
Week 52 | 1 (1·59%) | 1 (·54%) | 1·00 |
Gabapentin | |||
Baseline | 9 (14·3%) | 9 (13·9%) | |
Week 4 | 6 (9.5%) | 4 (6.2%) | 0·53 |
Week 24 | 12 (19·05%) | 14 (21·54%) | 0·73 |
Week 52 | 11 (17·46%) | 12 (18·46%) | 0·88 |
Based on receipt of disulfiram, acamprosate, naltrexone, topiramate, baclofen, and/or gabapentin.