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vRNA structures. The complete flaviviral genome contains a single open reading frame (gray) representing ten viral proteins. The flanking 5′‐ and 3′‐UTRs contain RNA elements of relevance to this review, which are annotated. An equilibrium between “linear” and “cyclized” forms is depicted. Upon cyclization, the 5′‐SLB structure is eliminated and the terminal 3′ structure is no longer associated with SL's stem.
