Table 1.

Summary of RdRp affinity and polymerase activity assays with various vRNA fragments

RNAs	Poly(N)	SLA	SLA tail	SL	cySL	SLA–SL	SLA–cySL	cyUTRs	5′ + 3′‐UTRs
2D structures
Polymerase activity	Yes44	No39	Yes39	No20, 21	n.d.	No39	Yes39	Yes20, 21	Yes (both 5′ and 3′ transcripts were observed)20, 21
RdRp‐binding activity	No39	Yes43 No39	Yes39	Yes40 No21	Yes20, 40	n.d.	n.d.	Yes40	n.d.
Free 3′‐tail following the long stem	Yes	No	Yes	No	Yes	No	Yes	Yes	Yes

n.d., not determined.

“cy” refers to structures as they would exist in cyclized form.

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