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. 2018 May 2;7(13):1701400. doi: 10.1002/adhm.201701400

Table 2.

Polymeric nanoparticles for antimicrobial drug delivery

Function Nanoparticle Drug Targeted microorganisms Activity and features Ref.
Antibacterial Poly‐lactic acid (PLA) Arjunglucoside Leishmania donovani
  • Reduced toxicity

74
Poly‐dl‐lactide‐co‐glycolide (PLGA) Gentamicin P. aeruginosa
  • Controlled antibiotic release

  • Improved antimicrobial effects

71
Poly‐dl‐glycolide (PLG) Econazole Moxifloxacin Mycobacterium tuberculosis
  • Prolonged therapeutic drug levels

  • Decreased dosage frequency

75
Polyethylene glycol (PEG)‐PLA Halofantrine Plasmodiumberghe
  • Extended blood circulation half‐life

76
Alginate Rifampicin Pyrazinamide Mycobacterium tuberculosis
  • Protection of drugs

  • Controlled drug release

  • Improved antimicrobial effects

77
Antifungal Poloxamer 188 coated poly(epsilon‐caprolactone)78 Amphotericin B Candida albicans
  • Decrease toxicity via reduced accumulation in liver and kidney

79
Antiviral β‐cyclodextrin‐poly(a‐acryloylmorpholine) Acyclovir HSV‐1 and HSV‐2
  • Improved antiviral activity

73
Polyhexycyanocrylate Saquinavir HIV
  • Improved delivery of antivirals

80

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