Table 4.

Solid lipid nanoparticles for antimicrobial drug delivery

Function	Encapsulant		Drug		Targeted microorganism	Activity and features	Ref.
	Natural	Synthetic	Natural	Synthetic
Antibacterial	Chitosan	Myristyl myristate	Tretinonin	–	Propionibacterium acnes, S. aureus	Improved drug loading capacity Greater stability No cytotoxicity in keratinocytes	103
	Stearic acid, soya phosphatidyl‐choline	–	–	Tobramycin	P. aeruginosa	Increase drug bioavailability	104
Antifungal	Glyceryl tripalmitate	Tyloxapol	–	Clotrimazole	Fungi	Controlled drug release Greater stability Improved drug loading capacity	105
	Glycerol palmitostearate	–	–	Miconazole nitrate	Fungi	Greater stability Improved drug loading capacity Improved drug penetration through stratum corneum	106
Antiviral	Stearic acid	–	–	Atazanavir	HIV	Improved drug loading capacity	107
	Egg phosphotidylcholine, glyceryl monostearate	–	–	Penciclovir	–	Improved targeting	108

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