Table 7.

Summary of methods for preparation of lipid‐based nanoparticles

Nanoparticles	Method	Formulation	Solvent	Stabilizer	Size [nm]	Ref.
	Microemulsion	Stearic acid	Methanol	Pluronic F68	167–224	122
	High pressure homogenization	Myristyl myristate	–	Pluronic F68	162.7 ± 1.4	123
Solid‐lipid NPs	Solvent emulsification‐evaporation	Para‐dodecanoyl‐calix[4]arene	Acetone, methanol, ethanol, glycerol	Pluronic F68	<60	124
	Solvent injection	Triglycerides	Acetone, methanol, ethanol, glycerol, isopropanol	Phosphatidylcholine, polysorbate 80, poloxamer 188	80–300	125
	Water‐in‐oil‐in‐water double emulsion	Stearic acid, dioctyl sodium sulfosuccinate, egg lecithin	–	–	–	126
	High shear homogenization	Benzyl nicotinate, hydrogenated soybean lecithin, cholesterol	–	Poloxamer 188, glycerol	240	127
	Membrane contactor	Propanol, glyceryl behenate	Sodium hydroxide	–	70–215	128
	Electrospray	Cholesterol	Ethanol	–	≈150
Nanostructured lipid carriers (NLC)	Solvent diffusion	Monostearic acid, caprylic triglycerides	Acetone, ethanol	Poloxamer 188	300–400	129
		Stearic acid, oleic acid	Acetone, ethanol	Poloxamer 188	160–430	130
	Melt‐emulsification and ultrasonication	Glyceryl behenate, polyoxyglycerides, Solutol HS‐15, C8‐C12 triglyceride, chitosan oligosaccharides	–	–	55–170	131

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