Skip to main content
. 2020 Apr 16;15(4):e0231716. doi: 10.1371/journal.pone.0231716

Fig 6. SpartaCas shows similar off-target reduction compared to eCas9 at two additional promiscuous loci.

Fig 6

(A) Off-targets found via GUIDE-seq with the guide DNMT1-4. (B) Off-targets found via GUIDE-seq with guide VEGFA site 2. The total height of bars indicates total off-targets identified. The cyan portion of bars indicates off-targets that remain present in each data set relative to wildtype but have reduced counts in GUIDE-seq analysis. Data is shown from a single GUIDE-seq experiment for each sample.