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. 2017 May 9;47(8):1007–1013. doi: 10.1111/cea.12935

Table 2.

Proportional hazards models of inflammatory markers at baseline and risk (hazard ratio, HR) of exacerbation (all exacerbations, and virus‐induced exacerbations)

Any exacerbation (n=22) Virus pos. exacerbation (n=15)
HR (95% CI) P‐value HR (95% CI) P‐value
FeNO >25 ppb 3.1 (1.2‐7.8) .015 3.4 (1.1‐10.4) .033
Sputum eosinophils >1% 4.1 (1.2‐13.8) .024 7.6 (1.6‐35.2) .010
Blood eosinophils >150 (×109 cells/L) 1.2 (0.5‐2.9) .720 1.0 (0.3‐3.0) .941
Atopy (positive SPT) 0.5 (0.2‐1.2) .129 0.6 (0.2‐1.6) .269
IgE >150 (×103 IU/L) 1.3 (0.5‐3.3) .648 1.4 (0.4‐4.5) .555

Each HR in the table represents a regression model adjusted for ICS dose, smoking status, ACQ score and % predicted FEV1 at baseline.

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