| Parameter | Ceftobiprole |
M1 |
||
|---|---|---|---|---|
| Day 1 | Day 5 | Day 1 | Day 5 | |
| Cmax (mg/L) | 29.2 (5.52) | 33.0 (4.83) | 0.804 (0.214) | 1.07 (0.254) |
| AUC0–8h (mg·h/L) | 90.0 (12.4) | 102 (11.9) | 3.68 (0.882) | 5.45 (1.35) |
| t1/2 (h) | 3.1 (0.3) | 3.3 (0.3) | 4.7 (0.8) | 5.8 (0.9) |
| CL (L/h) | 4.89 (0.687) | 4.98 (0.582) | − | − |
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