| Neisseria meningitidis strains and clinical parameters of IMD | TNF-α (ng/mL) | IL-1β (ng/mL) | IL-6 (ng/mL) |
|---|---|---|---|
| 137/05 group C strain | 3,724 | 5,844 | 8,071 |
| (C:NT:P1.2,5; ST-11 HC) M+S, APACHE 14, SOFA 3, moderate course | ±1,326 | ±3,556 | ±7,138 |
| 285/05 group B strain | 13,540 | 18,773 | 45,319 |
| (B:1:NST; ST-41/44 complex) M+S, APACHE 10, SOFA 4, mild course | ±4,038 | ±4,223 | ±14,563 |
| 113/04 group B strain | 10,908 | 15,661 | 37,123 |
| (B:22:P1.14; ST-18 HC) SS+WFS, APACHE 25, SOFA 12, severe course | ±3,043 | ±6,283 | ±14,575 |
| 109/05 group B strain | 3,399 | 6,664 | 10,493 |
| (B:NT:NST; ST-919, not HC) M+S, APACHE 17, SOFA 6, mild course | ±1,999 | ±4,290 | ±7,686 |
| 171/05 group B strain | 14,043 | 19,862 | 46,854 |
| (B:15:P1.4; ST-5126, not HC) M, APACHE 11, SOFA 3, mild course | ±4,103 | ±9,660 | ±14,629 |
HC: hypervirulent complex; IMD: invasive meningococcal disease; M: meningitis;
S: sepsis; SS: septic shock; WFS: Waterhouse–Friderichsen syndrome.
Data are expressed as mean±SD.