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. 2014 Dec 24;13:S109–S608. doi: 10.1111/j.1469-0691.2007.01733.x
Neisseria meningitidis strains and clinical parameters of IMD TNF-α (ng/mL) IL-1β (ng/mL) IL-6 (ng/mL)
137/05 group C strain 3,724 5,844 8,071
(C:NT:P1.2,5; ST-11 HC) M+S, APACHE 14, SOFA 3, moderate course ±1,326 ±3,556 ±7,138
285/05 group B strain 13,540 18,773 45,319
(B:1:NST; ST-41/44 complex) M+S, APACHE 10, SOFA 4, mild course ±4,038 ±4,223 ±14,563
113/04 group B strain 10,908 15,661 37,123
(B:22:P1.14; ST-18 HC) SS+WFS, APACHE 25, SOFA 12, severe course ±3,043 ±6,283 ±14,575
109/05 group B strain 3,399 6,664 10,493
(B:NT:NST; ST-919, not HC) M+S, APACHE 17, SOFA 6, mild course ±1,999 ±4,290 ±7,686
171/05 group B strain 14,043 19,862 46,854
(B:15:P1.4; ST-5126, not HC) M, APACHE 11, SOFA 3, mild course ±4,103 ±9,660 ±14,629

HC: hypervirulent complex; IMD: invasive meningococcal disease; M: meningitis;

S: sepsis; SS: septic shock; WFS: Waterhouse–Friderichsen syndrome.

Data are expressed as mean±SD.