Activity of telavancin against Staphylococcus aureus (SA) and coagulase-negative staphylococci (CoNS) isolates
| Organism | Specimen sourcea | Phenotypeb | No. of isolates | MIC (mg/L) |
|
|---|---|---|---|---|---|
| Range | MIC90 | ||||
| SA | SST | All | 951 | ≤0.015–1 | 0.25 |
| OX-S | 709 | ≤0.015–1 | 0.25 | ||
| OX-R | 242 | 0.06–1 | 0.5 | ||
| Blood | All | 365 | 0.06–1 | 0.25 | |
| OX-S | 235 | 0.06–1 | 0.25 | ||
| OX-R | 130 | 0.12–1 | 0.5 | ||
| LRT | All | 349 | ≤0.015–1 | 0.5 | |
| OX-S | 209 | ≤0.015–1 | 0.25 | ||
| OX-R | 140 | 0.12–1 | 0.5 | ||
| URT | All | 17 | 0.12–0.5 | 0.5 | |
| OX-S | 16 | 0.12–0.5 | 0.25 | ||
| OX-R | 1 | 0.5–0.5 | NAd | ||
| CoNS | SST | All | 25 | 0.06–0.25 | 0.25 |
| OX-S | 10 | 0.06–0.25 | 0.25 | ||
| OX-R | 15 | 0.12–0.25 | 0.25 | ||
| Blood | All | 190 | 0.06–2 | 0.5 | |
| OX-S | 48 | 0.12–2 | 0.5 | ||
| OX-R | 142 | 0.06–2 | 0.5 | ||
c 39 SA isolates and 11 CoNS isolates were from an unknown or other source.
a
SST, skin structure; LRT, lower respiratory tract; URT, upper respiratory tract.
b
OX-R, oxacillin-resistant; OX-S, oxacillin-susceptible.
d
Not available; MIC90 values were not determined for <10 isolates.