Table 1.
In vitro activities of some antibiotics against multi-resistant bloodstream infections of Acinetobacter spp.
| Antibiotics | MIC |
% Resistance |
|||
|---|---|---|---|---|---|
| MIC50 | MIC90 | Range | 1996–2000 (n = 60) | 2001–2005 (n = 104) | |
| Amikacin | 128 | 256 | 0.25–256 | 86.0 | 74.0 |
| Netilmicin | 4 | 32 | 0.125–64 | 46.7 | 25.0 |
| Imipenem | 32 | >32 | 0.064->32 | 65.0 | 63.5 |
| Piperacillin-tazobactam | 256 | >256 | 0.016->256 | 81.7 | 84.6 |
| Cefoperazone-sulbactam | 256 | 256 | 0.125->256 | 68.3 | 63.5 |
| Colistine | 2 | 1024 | 0.19–1024 | 63.3 | 25.0 |
| Tigecycline | 1 | 2 | 0.047–16 | 1.0 | |
| Ciprofloxacin | 32 | >32 | 0.064->32 | 66.7 | 83.7 |
| Tetracycline | 32 | 256 | 0.125->256 | 91.7 | 86.5 |