Prevaccine (N = 65)	Postvaccine (N = 53)	p
Age (years±SD)	65±17.8	63.4±20.2	0.9
Diabetes n (%)	6 (9.2)	5 (9.4)	0.61
Immunosuppression n (%)	5 (7.7)	1 (1.9)	0.16
Cirrhosis n (%)	9 (9.2)	2 (3.8)	0.21
Renal Chronic failure n (%)	1 (1.5)	0	0.56
Charlson index	0.74±0.94	0.94±1.14	0.49
Pneumonia n (%)	54 (83)	41 (77)	0.3
Meningitis n (%)	4 (6.2)	6 (11.3)	0.25
Exitus n (%)	6 (9.2)	7 (13.2)	0.35
Penicillin susceptible n (%)	50 (76.9)	50 (94.3)	0.007
Incidence ×106 year	9.22±3.48	6.12±2.04	0.14
BP× 103/hospital admissions	2.13±0.17	1.14±0.39	0.03
BP× 103/blood cultures	10.54±3.56	4.96±1.6	0.02