| Intracisternal injection | Bacterial count in CSF (cfu/mL) | Calorimetric TTP (h) | Peak heat flow (μW) |
|---|---|---|---|
| S. pneumoniae (n = 5) | 1.5×108 ±5.5×107 | 1.5±0.2 | 331±31 |
| N. meningitidis (n = 5) | 1.3×106 ±2.6×105 | 1.7±0.3 | 79±9 |
| heat-inactivated (n = 2) | 0 | Negative | <10 |
| Saline control (n = 2) | 0 | Negative | <10 |
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