Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Oct 18;9(4):875–890. doi: 10.1111/j.1462-5822.2006.00837.x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

PMC Copyright notice

Ultrastructural analysis of CPVs in replicon‐transfected and RUB‐infected cells by conventional processing for thin‐section and EM (BHK‐21 cells transfected with RUBrep/C‐GFP/neo after drug selection). A and B. Conventional EM shows two views of electron‐dense CPVs in perinuclear areas of replicon‐transfected cells. Internal vesicles (V) and straight elements (arrows) are denoted as are locally recruited organelles, RER and mitochondria (mi). The CPVs in B appear to be side views of the CPVs while in A, a frontal view of the CPV is shown. C and D. CPVs in RUB‐infected BHK cells 24 (C) and 48 (D) hours post infection. C is a higher magnification while D is a lower magnification. CPVs in infected cells contain both vesicles and straight elements (arrows). Inset in D shows a characteristic dense lysosome in a control cell. V, vesicles; N, nucleus. Bars: 200 nm in A–C; 0.5 μm in D.