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. 2015 Jan 8;20(12):O1059–O1066. doi: 10.1111/1469-0691.12749

TABLE 2.

Concordance data between PLEX‐ID and standard methods

Variable Data (%)
Concordance
 Overall concordance 45/101 (45)
 Concordance when excluding discordance for commensal oral flora 67/101 (66)
 Overall concordance among specimens from patients diagnosed with pneumonia post‐bronchoscopy 12/41 (30)
 Concordance among specimens from patients diagnosed with pneumonia post‐bronchoscopy, excluding commensal flora 22/41 (54)
 Discordance only at species level (genus identified by both methods) 2/101 (2)
Undetected organisms and resistance
 Among all organisms detected, number not detected by PLEX‐ID 43/218 (20)
 Among all organisms detected, number not detected by SM 46/218 (21)
 Among all organisms detected by SM, the number not detected by PLEX‐ID
  • 43/183 (24)

  • 51/191 (26.7), p <0.001

 Among all organisms detected by PLEX‐ID, the number not detected by SM
 Among non‐commensals detected by SM, number not detected by PLEX‐ID
  • 24/68 (35)

  • 26/70 (37), p <0.001

 Among non‐commensals detected by PLEX‐ID, number not detected by SM
 Among fungi detected by SM, number not detected by PLEX‐ID
  • 6/21 (28.6)

  • 15/30 (50), p 0.030

 Among fungi detected by PLEX‐ID, number not detected by SM
 Organisms most often ‘missed’ by PLEX‐ID, n (%)
Pneumocystis jirovecii 5/7 (71)
Actinomyces odontolyticus 4/18 (22)
Haemophilus influenzae 2/7 (29)
Escherichia coli 2/5 (40)
 Organisms most often ‘missed’ by standard methods, n (%)
Candida albicans 8/16 (50)
Streptococcus spp. 5/15 (33)
Streptococcus pneumoniae 5/6 (83)
Streptococcus group mitis (excluding S. pneumoniae) 3/22 (14)
 ‘Missed’ organisms, fungi, n (%)
 PLEX‐ID 6/36 (17)
 SM 15/36 (42), p 0.030
mecA identification (%)a
 PLEX‐ID 7/7 (100)
 SM 2/7 (29)

SM, standard methods.

a

No other resistance genes were identified throughout the study.