Figure 5.

Tarin putative targets in hematopoietic or cancer cells. The in vitro and in vivo mitogenic and cytokine release effects previously reported for tarin are summarized in the panel bone marrow effects and peripheral effects, while antitumoral/antimetastatic effects are represented in the panel molecular targets (cancer cell). The panel molecular targets rises the possibility of tarin binding to cell surface carbohydrates, present in hematopoietic or cancer cells. As a result, hematopoietic cells could be activated (left‐hand panel) and inflammatory signaling from cancer cells could be down‐regulated favoring the antitumoral responses (right‐hand panel). This is a representative figure. Cells and structures are not scaled.