Table 3.

Cytokines and Receptors

Protein	PDB entrya	References
Four‐helix bundle cytokines
Long chain, G‐CSF	1rhg	Hill et al. (1993)
Short chain, IL‐4	1rcb	Rozwarski et al. (1994), Smith et al. (1994)
Interferon‐γ‐like	1rfb	Ealick et al. (1991)
IL‐10	1ilk	Zdanov et al. (1995)
β‐trefoil cytokines
IL‐1α	2ila	Graves et al. (1990)
IL‐1β	1hib	Clore and Gronenborn (1991), Priestle et al. (1989)
Fibroblast growth factor	4fgf	Eriksson et al. (1991)
	2fgf	Zhang et al. (1991)
	1bas, 1bar	Zhu et al. (1991)
Cystine‐knot cytokines
TGF‐β	2tgi	Daopin et al. (1992, 1993), Schlunegger and Grutter (1993)
Nerve growth factor	1bet	McDonald et al. (1991)
Platelet‐derived growth factor Bb	1pdg	Oefner et al. (1992)
Human chorionic gonadotropin	1hrp, 1hcn	Lapthorn et al. (1994), Wu et al. (1994)
Chemokines
IL‐8	1il8	Clore et al. (1990)
MIP‐1β	1hum	Lodi et al., 1994
RANTES	1rto	Skelton et al. (1995)
Neutrophil activating peptide‐2	1nap	Malkowski et al. (1995)
TNF receptor superfamily
TNFR	1tnr	Banner et al. (1993)
TRAIL	1d4v	Mongkolsapaya et al. (1999)
Receptors for cystine‐knot growth factors
ActRII	1bte	Greenwald et al. (1999)
BRIA	1es7	Kirsch et al. (2000)
TBRII	1ktz	Hart et al. (2002)
TrkA	1www	Wiesmann et al. (1999)
Domain 2 of Flt‐1	1flt	Wiesmann et al. (1997)
Nuclear receptors
TR	1bsx	Darimont et al. (1998)
RAR	2lbd	Renaud et al. (1995)
ER	2ert	Shiau et al. (1998)
PR	1a28	Williams and Sigler (1998)
PPAR	1kkq	Xu et al. (2002)
Importin‐α	1ial	Kobe (1999)
Importin‐β	1qgr	Cingolani et al. (1999)
Adhesion receptors
Integrin I domain (LFA‐1)	1lfa	Qu and Leahy (1995)
Integrin I domain (CR3)	1ido	Lee et al. (1995)
Integrin (intact)	1jv2	Xiong et al. (2001)
β‐catenin/E‐cadherin	1i7x	Huber and Weis (2001)
β‐catenin/Tcf	1g3j	Graham et al. (2000)
Cysteine‐rich scavenger receptor
SRCR domain of Mac‐2 binding protein	1by2	Hohenester et al. (1999)
Glutamate receptors
iGluR	1gr2	Armstrong et al. (1998)
mGluR	1ewt, 1ewv	Kunishima et al. (2000)
Transferrin receptor
Human transferrin receptor	1cx8	Lawrence et al. (1999)

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