Table 8.
Aminoacyl‐t RNA Synthetases
Protein |
Subunits |
PDB entriesa |
---|---|---|
Class I | ||
Subclass Ia | ||
ArgRS |
α |
1bs2, 1f7u, 1f7v, 1iq0 |
CysRS |
α |
li5, 1li7 |
IleRS |
α |
1ile, 1ffy, 1jzq, 1jzs, 1qu2, 1qu3 |
LeuRS |
α |
1h3n |
MetRS |
α, α2 |
1a8h, 1f4l, 1qqt |
ValRS |
α |
1gax |
LysRS Ib |
α |
1irx |
Subclass Ib | ||
GlnRS |
α |
1euq, 1euy, 1exd, 1gsg, 1gtr, 1gts, 1qrs, 1qrt, 1qru, 1qtq |
GluRS |
α |
1g59, 1gln |
Subclass Ic | ||
TrpRS |
α2 |
1d2r, 1i6k, 1i6l, 1i6m, 1m83, 1mau, 1maw, 1mb2 |
TyrRS |
α2 |
1tya, 1tyb, 1tyc, 1tyd, 1h3f, 1jii, 1jij, 1jik, 1jil, 2ts1, 3ts1, 4ts1, 1h3e |
Class II | ||
Subclass IIa | ||
GlyRSc |
α2 |
1ati, 1b76, 1ggm |
HisRS |
α2 |
1h4v, 1qe0, 1adj, 1ady, 1htt, 1kmm, 1kmn |
ProRS |
α2 |
1hc7, 1h4q, 1h4s, 1h4t |
SerRS |
α2 |
1sry, 1ser, 1ses, 1set |
ThrRS |
α2 |
1evk, 1evl, 1fyf, 1kog, 1qf6 |
Subclass IIb | ||
AspRS |
α2 |
1l0w, 1b8a, 1eov, 1eqr, 1g51, 1asy, 1asz, 1coa, 1efw, 1il2 |
AsnRS |
α2 |
11as, 12as |
LysRS IIb |
α2 |
1bbw, 1bbu, 1e1o, 1e1t, 1e22, 1e24, 1lyl |
Subclass IIc | ||
PheRS |
(αβ)2 |
1ehz, 1pys, 1b70, 1b7y, 1eiy, 1jjc |
AlaRSc |
α4, α |
–c |
GlyRSd |
(αβ)2 |
–c |
There are both class I and class II LysRS
As of 2003, structures have not been determined.
GlyRS is found in two subclasses: IIa and IIc.
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