Table 14.

Enzymes

Protein	PDB entrya	Reference
α/β Hydrolases
Haloalkane dehaologenase	2had	Franken et al. (1991)
Torpedo californica acetylcholinesterase	1ack	Sussman et al. (1991)
Pseudomonas glumae triacylglycerol lipase	1tah	Noble et al. (1993)
Sialidases
Influenza A neuraminidase	1nn2	Varghese and Colman (1991)
Influenza B neuraminidase	1nsb	Burmeister et al. (1992)
Salmonella typhimurium LT2 sialidase	1dil	Crennell et al. (1993)
TIM barrel fold
Chicken muscle triose phosphate isomerase	1tim	Banner et al. (1975)
Serine proteases
Trypsin‐like
α‐Chymotrypsin	2cha	Birktoft and Blow (1972)
Subtilisins
Subtilisin BPN′	1sbt	Alden et al. (1971)
Serine carboxypeptidases
Wheat carboxypeptidase II	1wht	Liao and Remington (1990)
Herpes‐like serine protease
Cytomegalovirus protease	1cmv, 1wpo, 1lay	Qiu et al. (1996), Shieh et al. (1996), Tong et al. (1996)
Cysteine proteases
Papain‐like
Papain	9pap	Kamphuis et al. (1984)
Caspases
ICE (Caspase‐1)	1ice	Wilson et al. (1994)
Viral trypsin‐like
Hepatitus A virus 3C proteinase	1hav	Allaire et al. (1994)
Aspartic proteases
Pepsin‐like
Human rennin	2ren	Sielecki et al. (1989)
Retroviral
HIV‐1 Aspartyl protease	2hvp	Navia et al. (1989)
Metalloproteases
Zincins
Thermolysin	4tln	Holmes and Matthews (1982)
Astacin	1ast	Bode et al. (1992)
Zinc‐dependent exopeptidases
Leucine aminopeptidase	1lap	Burley et al. (1990)
Bovine carboxypeptidase A	5cpa	Rees et al. (1983)
Proteasome (Ntn hydrolase fold)
Archeon T. acidophilum 20S proteasome	1pma	Lowe et al. (1995)
Yeast 20S proteasome	1ryp	Groll et al. (1997)
Bovine 20S proteasome	1iru	Unno et al. (2002)
E. coli HslV	1ned	Bochtler et al. (1997)
Proteins in the ubiquitin pathway
Ubiquitin	1ubq	Vijay‐Kumar et al. (1987)
c‐Cbl‐UbcH7	1fbv	Zheng et al. (2000)
Ubc9‐RanGAP1	1kps	Bernier‐Villamor et al. (2002)
Siah	1k2f	Polekhina et al. (2002)
hMms2‐Ubc13	1j74, 1j7d	Moraes et al. (2001)
Mms2‐Ubc13	1jat	VanDemark et al. (2001)
Skp1‐Skp2	1fs2, 1fqv	Schulman et al. (2000)
Cul1‐Rbx1‐Skp1‐F‐box‐Skp2	1ldd, 1ldj, 1ldk	Zheng et al. (2002)

^aSee Web‐Based Structural Bioinformatics and http://www.rcsb.org/pdb.

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