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. 2020 Apr 16;15(4):e0231439. doi: 10.1371/journal.pone.0231439

Table 1. Relationship between CXL and baseline examination data (multiple logistic regression analysis).

Factors Wald score P-value 95%CI
Age 11.695 0.001 0.080–0.446
Gender 0. 037 0. 847 -0.510–0.919
History of atopic dermatitis 2.705 0.100 -0.832–0.994
Age on diagnosis 6.275 0.012 -0.305–0.071
BSCVA 0.482 0.488 -2.936–2.898
Manifest cylinder value 1.544 0.214 -0.265–0.389
Manifest spherical equivalent 0.848 0.357 -0.237–0.152
IOP 0.044 0. 834 -0.218–0.204
K2 on the anterior float 2.001 0.157 -2.427–1.384
K2 on the posterior float 1.678 0.195 -1.787–2.956
Total K2 2.112 0.146 -1.430–2.362
ISV 5.802 0.016 -0.112–0.142
IVA 7.036 0.008 -12.199–2.302
KI 4.665 0.031 -2.816–39.619
CKI 2.936 0.087 -7.378–35.953
IHA 0.229 0.632 -0.013–0.032
IHD 6.455 0.011 -29.139–14.853
Rmin 7.380 0.007 -1.014–6.718
TKC; 2 and below vs 2–3 or more 7.828 0.005 -57498.416–57456.610
TKC; 0 vs possible or more 8.607 0.014 -2.650–4.141
TKC; 1–2 or below vs 2 8.996 0.029 -1.244–5.877
TKC; possible vs 1 and 1–2 9.389 0.052 -5.458–2.029
TKC; 1 vs 1–2 9.500 0.091 -3.733–1.680
TKC; 2–3 vs 3 or more 8.350 0.015 -1.897–3.441
TKC; 3 vs 3–4 and 4 8.439 0.038 -1.691–5.393
TKC; 3–4 vs 4 8.439 0.077 -10.601–2.494
CCT 0.952 0.329 -0.037–0.028
TCT 1.879 0.171 -0.037–0.026

CXL, corneal cross-linking; BSCVA, best spectacle-corrected visual acuity; IOP, intraocular pressure; K2, the steepest keratometric value indicated by Pentacam® HR; ISV, index of surface variance; IVA, index of vertical asymmetry; KI, keratoconus index; CKI, center KI; IHA, index of height asymmetry; IHD, index of height decentration; Rmin, the minimum sagittal curvature evaluated by Pentacam®; TKC, topographic keratoconus classification; CCT, central corneal thickness; TCT, thinnest corneal thickness; 95% CI, 95% confidence interval.